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Tylosin is a macrolide antibiotic, a polyketide lactone substituted with three deoxyhexose sugars. It is used as an antimicrobial growth promoter in animals. Acquired resistance has been observed in potentially human pathogenic strains isolated from animals [1]. Among strains of Enterococcus faecium, resistance against tylosin was mainly detected in strains from poultry, but also in some strains from pork. Among strains of E. faecium and Enterococcus faecalis
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